N. hopelessness, despair, desperation, despondency, depression, pessimism, pessimist, job's comforter, bird of bad omen, bird of ill omen, abandonment, desolation, resignation, surrender, submission, hope deferred, dashed hopes, vain expectation, airy hopes &c, forlorn hope, gone case, dead duck, gone coon*, goner*, bad job, bad business, enfant perdu, gloomy horizon, black spots in the horizon, slough of despond, cave of despair, immedicabile vulnus

V. despair, lose all hope, give up all hope, abandon all hope, relinquish all hope, lose the hope of, give up the hope of, abandon the hope of, relinquish the hope of, give up, give over, yield to despair, falter, despond, jeter le manche apres la cognee, inspire despair, drive to despair, disconcert, dash one's hopes, crush one's hopes, destroy one's hopes, hope against hope, abandon, resign, surrender, submit

Adj. hopeless, desperate, despairing, gone, in despair, au desespoir, forlorn, desolate, inconsolable, broken hearted, unpromising, unpropitious, inauspicious, ill-omened, threatening, clouded over, out of the question, not to be thought of, impracticable, past hope, past cure, past mending, past recall, at one's last gasp, given up, given over, incurable, cureless, immedicable, remediless, beyond remedy, incorrigible, irreparable, irremediable, irrecoverable, irreversible, irretrievable, irreclaimable, irredeemable, irrevocable, ruined, undone, immitigable

Phr. "lasciate ogni speranza voi ch'entrate", its days are numbered, the worst come to the worst, "no change, no pause, no hope, yet i endure", "o dark, dark, dark, amid the blaze of noon", "mene mene tekel upharson"