N. hole, foramen, puncture, perforation, fontanel, transforation, pinhole, keyhole, loophole, porthole, peephole, mousehole, pigeonhole, eye of a needle, eyelet, slot, opening, aperture, apertness, hiation, yawning, oscitancy, dehiscence, patefaction|, pandiculation, chasm, embrasure, window, casement, abatjour, light, sky light, fan light, lattice, bay window, bow window, oriel, dormer, lantern, outlet, inlet, vent, vomitory, embouchure, orifice, mouth, sucker, muzzle, throat, gullet, weasand, wizen, nozzle, placket, portal, porch, gate, ostiary|, postern, wicket, trapdoor, hatch, door, arcade, cellarway, driveway, gateway, doorway, hatchway, gangway, lich gate, way, path, thoroughfare, channel, passage, passageway, tube, pipe, water pipe, air pipe, vessel, tubule, canal, gut, fistula, adjutage, ajutage, ostium, smokestack, chimney, flue, tap, funnel, gully, tunnel, main, mine, pit, adit, shaft, gallery, alley, aisle, glade, vista, bore, caliber, pore, blind orifice, fulgurite, thundertube, porousness, porosity, sieve, cullender, colander, cribble, riddle, screen, honeycomb, apertion, perforation, piercing, terebration, empalement, pertusion|, puncture, acupuncture, penetration, key, opener, master key, password, combination, passe-partout

V. open, ope, gape, yawn, bilge, fly open, perforate, pierce, empierce|, tap, bore, drill, mine, tunnel, transpierce, transfix, enfilade, impale, spike, spear, gore, spit, stab, pink, puncture, lance, stick, prick, riddle, punch, stave in, cut a passage through, make way for, make room for, uncover, unclose, unrip, lay open, cut open, rip open, throw open, pop open, blow open, pry open, tear open, pull open

Adj. open, perforated, perforate, wide open, ajar, unclosed, unstopped, oscitant, gaping, yawning, patent, tubular, cannular, fistulous, pervious, permeable, foraminous, vesicular, vasicular, porous, follicular, cribriform, honeycombed, infundibular, riddled, tubulous, tubulated, piped, tubate, opening, aperient

Int. open sesame

N. cleanness, cleanliness, purity, cleaning, purification, defecation, purgation, lustration, detersion, abstersion, epuration, mundation|, ablution, lavation, colature|, disinfection, drainage, sewerage, lavatory, laundry, washhouse, washerwoman, laundress, dhobi, laundryman, washerman, scavenger, dustman, sweep, white wings brush, broom, besom, mop, rake, shovel, sieve, riddle, screen, filter, blotter, napkin, cloth, maukin|, malkin|, handkerchief, towel, sudary, doyley, doily, duster, sponge, mop, swab, cover, drugget, wash, lotion, detergent, cathartic, purgative, purifier, disinfectant, aperient, benzene, benzine benzol, benolin, bleaching powder, chloride of lime, dentifrice, deobstruent, laxative

V. be clean, render clean &c

Adj. clean, clean, cleanly, cleanse, pure, mundify|, immaculate, rinse, spotless, wring, stainless, flush, taintless, full, trig, wipe, without a stain, mop, unstained, sponge, unspotted, scour, unsoiled, swab, unsullied, scrub, untainted, brush up, uninfected, wash, sweet, lave, sweet as a nut, launder, neat, buck, spruce, absterge|, tidy, deterge, trim, decrassify, gimp, clear, clean as a new penny, purify, like a cat in pattens, depurate, cleaned, despumate, kempt, defecate, abstergent, purge, cathartic, expurgate, cleansing, elutriate, purifying, lixiviate, edulcorate, clarify, refine, rack, filter, filtrate, drain, strain, disinfect, fumigate, ventilate, deodorize, whitewash, castrate, emasculate, sift, winnow, pick, weed, comb, rake, brush, sweep, rout out, clear out, sweep out &c, make a clean sweep of

Adv. neatly, clean as a whistle

N. remedy, help, cure, redress, medicine, medicament, diagnosis, medical examination, medical treatment, surgery, preventive medicine, clinical thermometer, stethoscope, x-ray machine, anthelmintic, antidote, antifebrile, antipoison, counterpoison, antitoxin, antispasmodic, bracer, faith cure, placebo, helminthagogue, lithagogue, pick-meup, stimulant, tonic, vermifuge, prophylactic, corrective, restorative, sedative, palliative, febrifuge, alterant, alterative, specific, antiseptic, emetic, analgesic, pain-killer, antitussive, antiinflammatory, antibiotic, antiviral, antifungal, carminative, nepenthe, mithridate, cure, treatment, regimen, radical cure, perfect cure, certain cure, sovereign remedy, examination, diagnosis, diagnostics, analysis, urinalysis, biopsy, radiology, medicine, physic, galenicals, simples, drug, pharmaceutical, prescription, potion, draught, dose, pill, bolus, injection, infusion, drip, suppository, electuary, linctus, lincture, medicament, pharmacon, nostrum, receipt, recipe, prescription, catholicon, panacea, elixir, elixir vitae, philosopher's stone, balm, balsam, cordial, theriac, ptisan, agueweed, arnica, benzoin, bitartrate of potash, boneset, calomel, catnip, cinchona, cream of tartar, epsom salts, feverroot, feverwort, friar's balsam, indian sage, ipecac, ipecacuanha, jonquil, mercurous chloride, peruvian bark, quinine, quinquina, sassafras, yarrow, salve, ointment, cerate, oil, lenitive, lotion, cosmetic, plaster, epithem, embrocation, liniment, cataplasm, sinapism, arquebusade, traumatic, vulnerary, pepastic, poultice, collyrium, depilatory, emplastrum, eyewater, vesicant, vesicatory, compress, pledget, bandage, treatment, medical treatment, regimen, dietary, dietetics, vis medicatrix, vis medicatrix naturae, medecine expectante, bloodletting, bleeding, venesection, phlebotomy, cupping, sanguisae, leeches, operation, surgical operation, transfusion, infusion, intravenous infusion, catheter, feeding tube, prevention, preventative medicine, immunization, inoculation, vaccination, vaccine, shot, booster, gamma globulin, pharmacy, pharmacology, pharmaceutics, pharmacopoeia, formulary, acology, materia medica, therapeutics, posology, homeopathy, allopathy, heteropathy, osteopathy, hydropathy, cold water cure, dietetics, surgery, chirurgery, chirurgy, healing art, leechcraft, orthopedics, orthopedy, orthopraxy, pediatrics, dentistry, midwifery, obstetrics, gynecology, tocology, sarcology, hospital, infirmary, pesthouse, lazarhouse, lazaretto, lock hospital, maison de sante, ambulance, dispensary, dispensatory, drug store, pharmacy, apothecary, druggist, chemist, hotel des invalides, sanatorium, spa, pump room, well, hospice, red cross, doctor, physician, surgeon, medical practitioner, general practitioner, specialist, medical attendant, apothecary, druggist, leech, osteopath, osteopathist, optometrist, ophthalmologist, internist, oncologist, gastroenterologist, epidemiologist, public health specialist, dermatologist, podiatrist, witch doctor, shaman, faith healer, quack, exorcist, aesculapius, hippocrates, galen, accoucheur, accoucheuse, midwife, oculist, aurist, operator, nurse, registered nurse, practical nurse, monthly nurse, sister, nurse's aide, candystriper, dresser, bonesetter, pharmaceutist, pharmacist, druggist, chemist, pharmacopolist

V. apply a remedy, doctor, dose, physic, nurse, minister to, attend, dress the wounds, plaster, drain, prevent, relieve, palliate, restore, drench with physic, bleed, cup, let blood, manicure, operate, excise, cut out, incise

Adj. remedial, restorative, corrective, palliative, healing, sanatory, sanative, prophylactic, preventative, immunizing, salutiferous, medical, medicinal, therapeutic, chirurgical, epulotic|, paregoric, tonic, corroborant, analeptic, balsamic, anodyne, hypnotic, neurotic, narcotic, sedative, lenitive, demulcent|, emollient, depuratory, detersive, detergent, abstersive, disinfectant, febrifugal, alterative, traumatic, vulnerary, allopathic, heteropathic, homeopathic, hydropathic, anthelmintic, antifebrile, antiluetic, aperient, chalybeate, deobstruent, depurative, laxative, roborant, dietetic, alimentary, nutritious, nutritive, peptic, alexipharmic, alexiteric, remediable, curable, phr, aux grands maux les grands remedes, dios que da la llaga da la medicina, para todo hay remedio sino para la muerte, temporis ars medicina fere est, "the remedy is worse than the disease", "throw physic to the dogs, i'll none of it"