N. disordered reason, disordered intellect, diseased mind, unsound mind, abnormal mind, derangement, unsoundness, psychosis, neurosis, cognitive disorder, affective disorder, insanity, lunacy, madness, mania, rabies, furor, mental alienation, aberration, paranoia, schizophrenia, dementation, dementia, demency, phrenitis, phrensy, frenzy, raving, incoherence, wandering, delirium, calenture of the brain, delusion, hallucination, lycanthropy, brain storm|, vertigo, dizziness, swimming, sunstroke, coup de soleil, siriasis, fanaticism, infatuation, craze, oddity, eccentricity, twist, monomania (caprice) 608, kleptodipsomania, hypochondriasis, melancholia, depression, clinical depression, severe depression, hysteria, amentia, screw loose, tile loose, slate loose, bee in one's bonnet, rats in the upper story, dotage

V. be insane, become insane, lose one's senses, lose one's reason, lose one's faculties, lose one's wits, go mad, run mad, lose one's marbles, go crazy, go bonkers, flip one's wig, flip one's lid, flip out, flip one's bush, rave, dote, ramble, wander, drivel, have a screw loose, have a devil, avoir le diable au corps, lose one's head, render mad, drive mad, madden, dementate, addle the wits, addle the brain, derange the head, infatuate, befool, turn the brain, turn one's head, drive one nuts

Adj. insane, mad, lunatic, loony, crazy, crazed, aliene, non compos mentis, not right, cracked, touched, bereft of reason, all possessed, unhinged, unsettled in one's mind, insensate, reasonless, beside oneself, demented, daft, phrenzied, frenzied, frenetic, possessed, possessed with a devil, deranged, maddened, moonstruck, shatterpated, mad-brained, scatter brained, shatter brained, crackbrained, touched, tetched, off one's head, maniacal, delirious, lightheaded, incoherent, rambling, doting, wandering, frantic, raving, stark staring mad, stark raving mad, wild-eyed, berserk, delusional, hallucinatory, corybantic, dithyrambic, rabid, giddy, vertiginous, wild, haggard, mazed, flighty, distracted, distraught, depressed, agitated, hyped up, bewildered, mad as a march hare, mad as a hatter, of unsound mind, touched in one's head, wrong in one's head, not right in one's head, not in one's right mind, not right in one's wits, upper story, out of one's mind, out of one's wits, out of one's skull, far gone, out of one's senses, out of one's wits, not in one's right mind, fanatical, infatuated, odd, eccentric, hypped, hyppish, spaced out, imbecile, silly, &c. 499

Adv. like one possessed

Phr. the mind having lost its balance, the reason under a cloud, tet exaltee, tet montee, ira furor brevis est, omnes stultos insanire

N. dejection, dejectedness, depression, prosternation|, lowness of spirits, depression of spirits, weight on the spirits, oppression on the spirits, damp on the spirits, low spirits, bad spirits, drooping spirits, depressed spirits, heart sinking, heaviness of heart, failure of heart, heaviness, infestivity, gloom, weariness, taedium vitae, disgust of life, mal du pays, anhedonia, melancholy, sadness, il penseroso, melancholia, dismals, blues, lachrymals, mumps, dumps, blue devils, doldrums, vapors, megrims, spleen, horrors, hypochondriasis, pessimism, la maladie sans maladie, despondency, slough of despond, disconsolateness, hope deferred, blank despondency, voiceless woe, prostration of soul, broken heart, despair, cave of despair, cave of trophonius demureness, gravity, solemnity, long face, grave face, hypochondriac, seek sorrow, self-tormentor, heautontimorumenos, malade imaginaire, medecin tant pis, croaker, pessimist, mope, mopus, affliction, sorry sight, memento mori, damper, wet blanket, job's comforter

V. be dejected, grieve, mourn, take on, give way, lose heart, despond, droop, sink, lower, look downcast, frown, pout, hang down the head, pull a long face, make a long face, laugh on the wrong side of the mouth, grin a ghastly smile, look blue, look like a drowned man, lay to heart, take to heart, mope, brood over, fret, sulk, pine, pine away, yearn, repine, despair, refrain from laughter, keep one's countenance, be grave, look grave, repress a smile, depress, discourage, dishearten, dispirit, damp, dull, deject, lower, sink, dash, knock down, unman, prostrate, break one's heart, frown upon, cast a gloom, cast a shade on, sadden, damp one's hopes, dash one's hopes, wither one's hopes, weigh on the mind, lie heavy on the mind, prey on the mind, weigh on the spirits, lie heavy on the spirits, prey on the spirits, damp the spirits, depress the spirits

Adj. cheerless, joyless, spiritless, uncheerful, uncheery, unlively, unhappy, melancholy, dismal, somber, dark, gloomy, triste, clouded, murky, lowering, frowning, lugubrious, funereal, mournful, lamentable, dreadful, dreary, flat, dull, dull as a beetle, dull as ditchwater, depressing, "melancholy as a gib cat", oppressed with melancholy, a prey to melancholy, downcast, downhearted, down in the mouth, down in one's luck, heavy-hearted, in the dumps, down in the dumps, in the suds, in the sulks, in the doldrums, in doleful dumps, in bad humor, sullen, mumpish, dumpish, mopish, moping, moody, glum, sulky, out of sorts, out of humor, out of heart, out of spirits, ill at ease, low spirited, in low spirits, a cup too low, weary, discouraged, disheartened, desponding, chapfallen, chopfallen, jaw fallen, crest fallen, sad, pensive, penseroso, tristful, dolesome, doleful, woebegone, lacrymose, lachrymose, in tears, melancholic, hypped, hypochondriacal, bilious, jaundiced, atrabilious, saturnine, splenetic, lackadaisical, serious, sedate, staid, stayed, grave as a judge, grave as an undertaker, grave as a mustard pot, sober, sober as a judge, solemn, demure, grim, grim-faced, grim-visaged, rueful, wan, long-faced, disconsolate, unconsolable, inconsolable, forlorn, comfortless, desolate, desole, sick at heart, soul sick, heart sick, au desespoir, in despair, lost, overcome, broken down, borne down, bowed down, heartstricken, cut up, dashed, sunk, unnerved, unmanned, down fallen, downtrodden, broken-hearted, careworn

Adv. with a long face, with tears in one's eyes, sadly

Phr. the countenance falling, the heart failing, the heart sinking within one, "a plague of sighing and grief", "thick-ey'd musing and curs'd melancholy", "the sickening pang of hope deferred"