N. painfulness, trouble, care, trial, affliction, infliction, blow, stroke, burden, load, curse, bitter pill, bitter draught, waters of bitterness, annoyance, grievance, nuisance, vexation, mortification, sickener, bore, bother, pother, hot water, "sea of troubles", hornet's nest, plague, pest, cancer, ulcer, sting, thorn, canker, scorpion, dagger, scourge, carking care, canker worm of care, mishap, misfortune, desagrement, esclandre, rub, source of irritation, source of annoyance, wound, open sore, sore subject, skeleton in the closet, thorn in the flesh, thorn in one's side, where the shoe pinches, gall and wormwood, sorry sight, heavy news, provocation, affront, "head and front of one's offending", infestation, molestation, malignity

V. cause pain, occasion pain, give pain, bring pain, induce pain, produce pain, create pain, inflict pain, pain, hurt, wound, pinch, prick, gripe, pierce, lancinate, cut, hurt the feelings, wound the feelings, grate upon the feelings, grate upon the nerves, jar upon the feelings, wring the heart, pierce the heart, lacerate the heart, break the heart, rend the heart, make the heart bleed, tear the heart strings, rend the heart strings, draw tears from the eyes, sadden, make unhappy, plunge into sorrow, grieve, fash, afflict, distress, cut up, cut to the heart, displease, annoy, incommode, discompose, trouble, disquiet, faze, feaze, feeze (u .s.), disturb, cross, perplex, molest, tease, tire, irk, vex, mortify, wherret|, worry, plague, bother, pester, bore, pother, harass, harry, badger, heckle, bait, beset, infest, persecute, importune, wring, harrow, torment, torture, bullyrag, put to the rack, put to the question, break on the wheel, rack, scarify, cruciate, crucify, convulse, agonize, barb the dart, plant a dagger in the breast, plant a thorn in one's side, irritate, provoke, sting, nettle, try the patience, pique, fret, rile, tweak the nose, chafe, gall, sting to the quick, wound to the quick, cut to the quick, aggrieve, affront, enchafe, enrage, ruffle, sour the temper, give offense, maltreat, bite, snap at, assail, smite, sicken, disgust, revolt, nauseate, disenchant, repel, offend, shock, stink in the nostrils, go against the stomach, turn the stomach, make one sick, set the teeth on edge, go against the grain, grate on the ear, stick in one's throat, stick in one's gizzard, rankle, gnaw, corrode, horrify, appal, appall, freeze the blood, make the flesh creep, make the hair stand on end, make the blood curdle, make the blood run cold, make one shudder, haunt the memory, weigh on the heart, prey on the heart, weigh on the mind, prey on the mind, weigh on the spirits, prey on the spirits, bring one's gray hairs with sorrow to the grave, add a nail to one's coffin

Adj. causing pain, hurting, hurtful, painful, dolorific, dolorous, unpleasant, unpleasing, displeasing, disagreeable, unpalatable, bitter, distasteful, uninviting, unwelcome, undesirable, undesired, obnoxious, unacceptable, unpopular, thankless, unsatisfactory, untoward, unlucky, uncomfortable, distressing, afflicting, afflictive, joyless, cheerless, comfortless, dismal, disheartening, depressing, depressive, dreary, melancholy, grievous, piteous, woeful, rueful, mournful, deplorable, pitiable, lamentable, sad, affecting, touching, pathetic, irritating, provoking, stinging, annoying, aggravating, mortifying, galling, unaccommodating, invidious, vexatious, troublesome, tiresome, irksome, wearisome, plaguing, plaguy, awkward, importunate, teasing, pestering, bothering, harassing, worrying, tormenting, carking, intolerable, insufferable, insupportable, unbearable, unendurable, past bearing, not to be borne, not to be endured, more than flesh and blood can bear, enough to drive one mad, enough to provoke a saint, enough to make a parson swear, enough to gag a maggot, shocking, terrific, grim, appalling, crushing, dreadful, fearful, frightful, thrilling, tremendous, dire, heart-breaking, heart-rending, heart-wounding, heart-corroding, heart-sickening, harrowing, rending, odious, hateful, execrable, repulsive, repellent, abhorrent, horrid, horrible, horrific, horrifying, offensive, nauseous, nauseating, disgusting, sickening, revolting, nasty, loathsome, loathful, fulsome, vile, hideous, sharp, acute, sore, severe, grave, hard, harsh, cruel, biting, caustic, cutting, corroding, consuming, racking, excruciating, searching, grinding, grating, agonizing, envenomed, catheretic, pyrotic, ruinous, disastrous, calamitous, tragical, desolating, withering, burdensome, onerous, oppressive, cumbrous, cumbersome

Adv. painfully, with pain, deuced

Int. hinc illae lachrymae, phr, surgit amari aliquid, the place being too hot to hold one, the iron entering into the soul, "he jests at scars that never felt a wound", "i must be cruel only to be kind", "what deep wounds ever closed without a scar?"

N. seclusion, privacy, retirement, reclusion, recess, snugness, delitescence, rustication, rus in urbe, solitude, solitariness, isolation, loneliness, estrangement from the world, voluntary exile, aloofness, cell, hermitage, convent, sanctum sanctorum, depopulation, desertion, desolation, wilderness, howling wilderness, rotten borough, old sarum, exclusion, excommunication, banishment, exile, ostracism, proscription, cut, cut direct, dead cut, inhospitality, inhospitableness, dissociability, domesticity, darby and joan, recluse, hermit, eremite, cenobite, anchoret, anchorite, simon stylites, troglodyte, timon of athens, santon, solitaire, ruralist, disciple of zimmermann, closet cynic, diogenes, outcast, pariah, castaway, pilgarlic, wastrel, foundling, wilding

V. be secluded, live secluded, keep aloof, stand, hold oneself aloof, keep in the background, stand in the background, keep snug, shut oneself up, deny oneself, seclude oneself creep into a corner, rusticate, aller planter ses choux, retire, retire from the world, take the veil, abandon, sport one's oak*, cut, cut dead, refuse to associate with, refuse to acknowledge, look cool upon, turn one's back upon, shut the door upon, repel, blackball, excommunicate, exclude, exile, expatriate, banish, outlaw, maroon, ostracize, proscribe, cut off from, send to coventry, keep at arm's length, draw a cordon round, depopulate, dispeople, unpeople

Adj. secluded, sequestered, retired, delitescent, private, bye, out of the world, out of the way, "the world forgetting by the world forgot", snug, domestic, stay-at-home, unsociable, unsocial, dissocial, inhospitable, cynical, inconversable|, unclubbable, sauvage, troglodytic, solitary, lonely, lonesome, isolated, single, estranged, unfrequented, uninhabitable, uninhabited, tenantless, abandoned, deserted, deserted in one's utmost need, unfriended, kithless, friendless, homeless, lorn, forlorn, desolate, unvisited, unintroduced, uninvited, unwelcome, under a cloud, left to shift for oneself, derelict, outcast, banished

Phr. noli me tangere, "among them but not of them", "and homeless near a thousand homes i stood", far from the madding crowd's ignoble strife, "makes a solitude and calls it peace", magna civitas magna solitudo, "never less alone than when alone", "o sacred solitude! divine retreat!"