N. disease, illness, sickness, ailing &c. "all the ills that flesh is heir to", morbidity, morbosity|, infirmity, ailment, indisposition, complaint, disorder, malady, distemper, distemperature, visitation, attack, seizure, stroke, fit, delicacy, loss of health, invalidation, cachexy, cachexia, atrophy, marasmus, indigestion, dyspepsia, decay, decline, consumption, palsy, paralysis, prostration, taint, pollution, infection, sepsis, septicity, infestation, epidemic, pandemic, endemic, epizootic, murrain, plague, pestilence, pox, sore, ulcer, abscess, fester, boil, pimple, wen, carbuncle, gathering, imposthume, peccant humor, issue, rot, canker, cold sore, fever sore, cancer, carcinoma, leukemia, neoplastic disease, malignancy, tumor, caries, mortification, corruption, gangrene, sphacelus, sphacelation, leprosy, eruption, rash, breaking out, fever, temperature, calenture, inflammation, ague, angina pectoris, appendicitis, asiatic cholera, spasmodic cholera, biliary calculus, kidney stone, black death, bubonic plague, pneumonic plague, blennorrhagia, blennorrhoea, blood poisoning, bloodstroke, bloody flux, brash, breakbone fever, dengue fever, malarial fever, q-fever, heart attack, cardiac arrest, cardiomyopathy, hardening of the arteries, arteriosclerosis, atherosclerosis, bronchocele, canker rash, cardialgia, carditis, endocarditis, cholera, asphyxia, chlorosis, chorea, cynanche, dartre, enanthem, enanthema, erysipelas, exanthem, exanthema, gallstone, goiter, gonorrhea, green sickness, grip, grippe, influenza, flu, hay fever, heartburn, heaves, rupture, hernia, hemorrhoids, piles, herpes, itch, king's evil, lockjaw, measles, mumps, polio, necrosis, pertussis, phthisis, pneumonia, psora, pyaemia, pyrosis, quinsy, rachitis, ringworm, rubeola, st. vitus's dance, scabies, scarlatina, scarlet fever, scrofula, seasickness, struma, syntexis, tetanus, tetter, tonsillitis, tonsilitis, tracheocele, trachoma, trismus, varicella, varicosis, variola, water qualm, whooping cough, yellow fever, yellow jack, fatal disease, dangerous illness, galloping consumption, churchyard cough, general breaking up, break up of the system, idiocy, insanity, martyr to disease, cripple, "the halt the lame and the blind", valetudinary, valetudinarian, invalid, patient, case, sickroom, sick- chamber, pathology, etiology, nosology, anthrax, bighead, blackleg, blackquarter, cattle plague, glanders, mange, scrapie, milk sickness, heartworm, feline leukemia, roundworms, quarter-evil, quarter-ill, rinderpest, virus, bacterium, bacteria, dna virus, rna virus, rhinovirus, rhabdovirus, picornavirus, herpesvirus, cytomegalovirus, cmv, human immunodefficiency virus, hiv

V. be ill, ail, suffer, labor under, be affected with, complain of, have, droop, flag, languish, halt, sicken, peak, pine, gasp, keep one's bed, feign sickness, lay by, lay up, take a disease, catch a disease, catch an infection, break out

Adj. diseased, ailing, ill, ill of, taken ill, seized with, indisposed, unwell, sick, squeamish, poorly, seedy, affected with illness, afflicted with illness, laid up, confined, bedridden, invalided, in hospital, on the sick list, out of health, out of sorts, under the weather, valetudinary, unsound, unhealthy, sickly, morbid, morbose, healthless, infirm, chlorotic, unbraced, drooping, flagging, lame, crippled, halting, morbid, tainted, vitiated, peccant, contaminated, poisoned, tabid, mangy, leprous, cankered, rotten, rotten to the core, rotten at the core, withered, palsied, paralytic, dyspeptic, luetic, pneumonic, pulmonic, phthisic, rachitic, syntectic, syntectical, tabetic, varicose, touched in the wind, broken-winded, spavined, gasping, hors de combat, weakly, weakened, decrepit, decayed, incurable, in declining health, cranky, in a bad way, in danger, prostrate, moribund, morbific, epidemic, endemic, zymotic

N. deterioration, debasement, wane, ebb, recession, retrogradation, decrease, degeneracy, degeneration, degenerateness, degradation, depravation, depravement, devolution, depravity, demoralization, retrogression, masochism, impairment, inquination|, injury, damage, loss, detriment, delaceration|, outrage, havoc, inroad, ravage, scath, perversion, prostitution, vitiation, discoloration, oxidation, pollution, defoedation|, poisoning, venenation|, leaven, contamination, canker, corruption, adulteration, alloy, decline, declension, declination, decadence, decadency, falling off, caducity, decrepitude, decay, dilapidation, ravages of time, wear and tear, corrosion, erosion, moldiness, rottenness, moth and rust, dry rot, blight, marasmus, atrophy, collapse, disorganization, delabrement &c. (destruction), 162, aphid, aphis, plant louse, puceron, vinefretter, vinegrub, wreck, mere wreck, honeycomb, magni nominis umbra, jade, plug, rackabones, skate, tackey, tacky

V. be worse, be deteriorated, become worse, become deteriorated, have seen better days, deteriorate, degenerate, fall off, wane, ebb, retrograde - decline, droop, go down, go downhill, go from bad to worse, go farther and fare worse, jump out of the frying pan into the fire, run to seed, go to seed, run to waste swale|, sweal|, lapse, be the worse for, sphacelate, break, break down, spring a leak, crack, start, shrivel, fade, go off, wither, molder, rot, rankle, decay, go bad, go to decay, fall into decay, "fall into the sear and yellow leaf", rust, crumble, shake, totter, totter to its fall, perish, die, deteriorate, weaken, put back, set back, taint, infect, contaminate, poison, empoison, envenom, canker, corrupt, exulcerate|, pollute, vitiate, inquinate|, debase, embase|, denaturalize, denature, leaven, deflower, debauch, defile, deprave, degrade, ulcerate, stain, discolor, alloy, adulterate, sophisticate, tamper with, prejudice, pervert, prostitute, demoralize, brutalize, render vicious, embitter, acerbate, exacerbate, aggravate, injure, impair, labefy, damage, harm, hurt, shend|, scath|, scathe, spoil, mar, despoil, dilapidate, waste, overrun, ravage, pillage, wound, stab, pierce, maim, lame, surbate|, cripple, hough, hamstring, hit between wind and water, scotch, mangle, mutilate, disfigure, blemish, deface, warp, blight, rot, corrode, erode, wear away, wear out, gnaw, gnaw at the root of, sap, mine, undermine, shake, sap the foundations of, break up, disorganize, dismantle, dismast, destroy, damnify, do one's worst, knock down, deal a blow to, play havoc with, play sad havoc with, play the mischief with, play the deuce with, play the very devil with, play havoc among, play sad havoc among, play the mischief among, play the deuce among, play the very devil among, decimate

Adj. unimproved &c. (improve ), deteriorated, altered, altered for the worse, injured, sprung, withering, spoiling, on the wane, on the decline, tabid, degenerate, marescent, worse, the worse for, all the worse for, out of repair, out of tune, imperfect, the worse for wear, battered, weathered, weather-beaten, stale, passe, shaken, dilapidated, frayed, faded, wilted, shabby, secondhand, threadbare, worn, worn to a thread, worn to a shadow, worn to the stump, worn to rags, reduced, reduced to a skeleton, far gone, tacky, decayed, moth-eaten, worm-eaten, mildewed, rusty, moldy, spotted, seedy, time-worn, moss-grown, discolored, effete, wasted, crumbling, moldering, rotten, cankered, blighted, tainted, depraved, decrepid, decrepit, broke, busted, broken, out of commission, hors de combat, out of action, broken down, done, done for, done up, worn out, used up, finished, beyond saving, fit for the dust hole, fit for the wastepaper basket, past work, at a low ebb, in a bad way, on one's last legs, undermined, deciduous, nodding to its fall, tottering &c, (dangerous) 665: past cure, fatigued, retrograde, deleterious

Phr. out of the frying pan into the fire, agrescit medendo, "what a falling off was there!"

N. bane, curse, evil, hurtfulness, painfulness, scourge, damnosa hereditas, white elephant, sting, fang, thorn, tang, bramble, brier, nettle, poison, toxin, teratogen, leaven, virus venom, arsenic, antimony, tartar emetic, strychnine, nicotine, miasma, miasm, mephitis, malaria, azote, sewer gas, pest, albany hemp, arsenious oxide, arsenious acid, bichloride of mercury, carbonic acid, carbonic gas, choke damp, corrosive sublimate, fire damp, hydrocyanic acid, cyanide, prussic acid, hydrogen cyanide, marsh gas, nux vomica, ratsbane, hemlock, hellebore, nightshade, belladonna, henbane, aconite, banewort, bhang, ganja, hashish, upas tree, toxline, rust, worm, helminth, moth, moth and rust, fungus, mildew, dry rot, canker, cankerworm, cancer, torpedo, viper, demon, toxicology

Adj. baneful, poisonous, phr, bibere venenum in auro, 3. contingent subservience

N. painfulness, trouble, care, trial, affliction, infliction, blow, stroke, burden, load, curse, bitter pill, bitter draught, waters of bitterness, annoyance, grievance, nuisance, vexation, mortification, sickener, bore, bother, pother, hot water, "sea of troubles", hornet's nest, plague, pest, cancer, ulcer, sting, thorn, canker, scorpion, dagger, scourge, carking care, canker worm of care, mishap, misfortune, desagrement, esclandre, rub, source of irritation, source of annoyance, wound, open sore, sore subject, skeleton in the closet, thorn in the flesh, thorn in one's side, where the shoe pinches, gall and wormwood, sorry sight, heavy news, provocation, affront, "head and front of one's offending", infestation, molestation, malignity

V. cause pain, occasion pain, give pain, bring pain, induce pain, produce pain, create pain, inflict pain, pain, hurt, wound, pinch, prick, gripe, pierce, lancinate, cut, hurt the feelings, wound the feelings, grate upon the feelings, grate upon the nerves, jar upon the feelings, wring the heart, pierce the heart, lacerate the heart, break the heart, rend the heart, make the heart bleed, tear the heart strings, rend the heart strings, draw tears from the eyes, sadden, make unhappy, plunge into sorrow, grieve, fash, afflict, distress, cut up, cut to the heart, displease, annoy, incommode, discompose, trouble, disquiet, faze, feaze, feeze (u .s.), disturb, cross, perplex, molest, tease, tire, irk, vex, mortify, wherret|, worry, plague, bother, pester, bore, pother, harass, harry, badger, heckle, bait, beset, infest, persecute, importune, wring, harrow, torment, torture, bullyrag, put to the rack, put to the question, break on the wheel, rack, scarify, cruciate, crucify, convulse, agonize, barb the dart, plant a dagger in the breast, plant a thorn in one's side, irritate, provoke, sting, nettle, try the patience, pique, fret, rile, tweak the nose, chafe, gall, sting to the quick, wound to the quick, cut to the quick, aggrieve, affront, enchafe, enrage, ruffle, sour the temper, give offense, maltreat, bite, snap at, assail, smite, sicken, disgust, revolt, nauseate, disenchant, repel, offend, shock, stink in the nostrils, go against the stomach, turn the stomach, make one sick, set the teeth on edge, go against the grain, grate on the ear, stick in one's throat, stick in one's gizzard, rankle, gnaw, corrode, horrify, appal, appall, freeze the blood, make the flesh creep, make the hair stand on end, make the blood curdle, make the blood run cold, make one shudder, haunt the memory, weigh on the heart, prey on the heart, weigh on the mind, prey on the mind, weigh on the spirits, prey on the spirits, bring one's gray hairs with sorrow to the grave, add a nail to one's coffin

Adj. causing pain, hurting, hurtful, painful, dolorific, dolorous, unpleasant, unpleasing, displeasing, disagreeable, unpalatable, bitter, distasteful, uninviting, unwelcome, undesirable, undesired, obnoxious, unacceptable, unpopular, thankless, unsatisfactory, untoward, unlucky, uncomfortable, distressing, afflicting, afflictive, joyless, cheerless, comfortless, dismal, disheartening, depressing, depressive, dreary, melancholy, grievous, piteous, woeful, rueful, mournful, deplorable, pitiable, lamentable, sad, affecting, touching, pathetic, irritating, provoking, stinging, annoying, aggravating, mortifying, galling, unaccommodating, invidious, vexatious, troublesome, tiresome, irksome, wearisome, plaguing, plaguy, awkward, importunate, teasing, pestering, bothering, harassing, worrying, tormenting, carking, intolerable, insufferable, insupportable, unbearable, unendurable, past bearing, not to be borne, not to be endured, more than flesh and blood can bear, enough to drive one mad, enough to provoke a saint, enough to make a parson swear, enough to gag a maggot, shocking, terrific, grim, appalling, crushing, dreadful, fearful, frightful, thrilling, tremendous, dire, heart-breaking, heart-rending, heart-wounding, heart-corroding, heart-sickening, harrowing, rending, odious, hateful, execrable, repulsive, repellent, abhorrent, horrid, horrible, horrific, horrifying, offensive, nauseous, nauseating, disgusting, sickening, revolting, nasty, loathsome, loathful, fulsome, vile, hideous, sharp, acute, sore, severe, grave, hard, harsh, cruel, biting, caustic, cutting, corroding, consuming, racking, excruciating, searching, grinding, grating, agonizing, envenomed, catheretic, pyrotic, ruinous, disastrous, calamitous, tragical, desolating, withering, burdensome, onerous, oppressive, cumbrous, cumbersome

Adv. painfully, with pain, deuced

Int. hinc illae lachrymae, phr, surgit amari aliquid, the place being too hot to hold one, the iron entering into the soul, "he jests at scars that never felt a wound", "i must be cruel only to be kind", "what deep wounds ever closed without a scar?"